General
Numer kat.	bs-1103R
Opis produktu:
Programmed cell death 1 ligand 1(Programmed death ligand 1?PD-L1; PDCD1 ligand 1; B7 homolog 1; B7-H1; CD274) involved in the costimulatory signal, essential for T lymphocyte proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibit T-cell proliferation and cytokine production. [SUBUNIT] Interacts with PDCD1. [SUBCELLULAR LOCATION] Isoform 1: Cell membrane; Single-pass type I membrane protein. Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes. Belongs to the immunoglobulin superfamily. BTN/MOG family.
Product Size
Ilość w opakowaniu	100ug Lyophilized
Producent	Bioss